A SIMPLE KEY FOR PKRRATING UNVEILED

3B). R526 within the loop between αJ and αI anchors the C-terminal percentage of the activation loop by forming a salt bridge with E458 at The bottom of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the most crucial chain carbonyl of R413. The suggestion with the activation phase is stabilized by a hydrogen bond amongst Y454 and E480